Synthesis, in silico and in vitro antimicrobial activity of N-(benzyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxamides

• Main Authors: Sergiy V. Vlasov (Author), Oleksandr V. Borysov (Author), Hanna I. Severina (Author), Vitaliy S. Vlasov (Author), Amjad Ibrahim M. Abu Sharkh (Author), Victoriya A. Georgiyants (Author)
• Format: Book
• Published: Pensoft Publishers, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

According to the recent studies bezylcarboxamide fragment attached to the thiophene ring of thieno[2,3-d]pyrimidine is beneficial for antimicrobial activity of the compounds. Therefore we focused our efforts on constructing of the simple molecules such as N-(benzyl)-5-methyl-4-oxo-3,4-dihydrothieno[...