Transforming Growth Factor-β3/Recombinant Human-like Collagen/Chitosan Freeze-Dried Sponge Primed With Human Periodontal Ligament Stem Cells Promotes Bone Regeneration in Calvarial Defect Rats

• Main Authors: Shiyi Huang (Author), Fenglin Yu (Author), Yating Cheng (Author), Yangfan Li (Author), Yini Chen (Author), Jianzhong Tang (Author), Yu Bei (Author), Qingxia Tang (Author), Yueping Zhao (Author), Yadong Huang (Author), Qi Xiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with a skull defect are at risk of developing cerebrospinal fluid leakage and ascending bacterial meningitis at >10% per year. However, treatment with stem cells has brought great hope to large-area cranial defects. Having found that transforming growth factor (TGF)-β3 can promote the os...