Liposome-Encapsulated Hemoglobin Ameliorates Impairment of Fear Memory and Hippocampal Dysfunction After Cerebral Ischemia in Rats

• Main Authors: Naobumi Hamadate (Author), Taku Yamaguchi (Author), Aya Sugawara (Author), Hiroko Togashi (Author), Takeshi Izumi (Author), Takayuki Yoshida (Author), Yu Ohmura (Author), Mitsuhiro Yoshioka (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Liposome-encapsulated hemoglobin (LEH) has been developed as a blood substitute. In spite of its size (1/30 - 1/40 of erythrocytes), LEH has an oxygen-carrying capacity comparable to erythrocytes. Thus, LEH is expected to carry oxygen into vital organs via collateral routes during ischemi...