Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase which plays a center role in the phosphorylation of a wide variety of proteins, generally leading to their inactivation. As such, GSK-3 is viewed as a therapeutic target. An ever-increasing number of small organic molecule inhibitors of...

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Main Authors: Nicholas O. Schneider (Author), Kendra Gilreath (Author), Daniel J. Burkett (Author), Martin St. Maurice (Author), William A. Donaldson (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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