Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity

Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity

Nucleic acid aptamers have attracted considerable attention as next-generation pharmaceutical agents and delivery vehicles for small molecule drugs and therapeutic oligonucleotides. Chemical modification is an effective approach for improving the functionality of aptamers. However, the process of se...

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Main Authors: Hiro Uemachi (Author), Yuuya Kasahara (Author), Keisuke Tanaka (Author), Takumi Okuda (Author), Yoshihiro Yoneda (Author), Satoshi Obika (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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