Polymeric nanoparticles containing rapamycin and autoantigen induce antigen-specific immunological tolerance for preventing vitiligo in mice

• 主要な著者: Xia Zhang (著者), Daji Liu (著者), Minghong He (著者), Mao Lin (著者), Caixia Tu (著者), Baoxiang Zhang (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2021-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Vitiligo is an autoimmune disease in which pigment is lost in patches of the skin. CD4+ T cells are implicated in vitiligo while regulatory T cells (Tregs) could ameliorate vitiligo. Rapamycin together with autoantigen have been shown to induce immunological tolerance and promote Tregs in multiple a...