Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice

• Main Authors: Aimée R. Bugler-Lamb (Author), Annie Hasib (Author), Xiong Weng (Author), Chandani K. Hennayake (Author), Chenshi Lin (Author), Rory J. McCrimmon (Author), Roland H. Stimson (Author), Michael L.J. Ashford (Author), David H. Wasserman (Author), Li Kang (Author)
• Format: Book
• Published: Elsevier, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Increased deposition of the extracellular matrix (ECM) in adipose tissue (AT) during obesity contributes to insulin resistance. The integrin receptors transmit changes in the extracellular environment causing corresponding intracellular adaptations. Integrin-linked kinase (ILK), an adapto...