Synthesis and Study of the Structure-Activity Relationship of Antiproliferative <i>N</i>-Substituted Isosteviol-Based 1,3-Aminoalcohols
Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis and rearrangement of natural stevioside produced isosteviol, which was transformed into the key intermediate methyl ester. In the next step,...
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MDPI AG,
2024-02-01T00:00:00Z.
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A1234.567 |
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