Mesoporous Silica Microparticle-Protein Complexes: Effects of Protein Size and Solvent Properties on Diffusion and Loading Efficiency

• Главные авторы: Mohamad Anas Al Tahan (Автор), Kyprianos Michaelides (Автор), Smith Somasekharan Nair (Автор), Shouq AlShatti (Автор), Craig Russell (Автор), Ali Al-Khattawi (Автор)
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• Опубликовано: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Предметы: article
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Oral administration of protein-based therapeutics is highly desirable due to lower cost, enhanced patient compliance, and convenience. However, the harsh pH environment of the gastrointestinal tract poses significant challenges. Silica-based carriers have emerged as potential candidates for the deli...