Mesoporous Silica Microparticle-Protein Complexes: Effects of Protein Size and Solvent Properties on Diffusion and Loading Efficiency

• Main Authors: Mohamad Anas Al Tahan (Author), Kyprianos Michaelides (Author), Smith Somasekharan Nair (Author), Shouq AlShatti (Author), Craig Russell (Author), Ali Al-Khattawi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oral administration of protein-based therapeutics is highly desirable due to lower cost, enhanced patient compliance, and convenience. However, the harsh pH environment of the gastrointestinal tract poses significant challenges. Silica-based carriers have emerged as potential candidates for the deli...