An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice

• Principais autores: Chuang-Wei Wang (Autor), Ivan Arni C. Preclaro (Autor), Wei-Hsiang Lin (Autor), Wen-Hung Chung (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Adverse drug reactions (ADR) remain the major problems in healthcare. Most severe ADR are unpredictable, dose-independent and termed as type B idiosyncratic reactions. Recent pharmacogenomic studies have demonstrated the strong associations between severe ADR and genetic markers, including specific...