Cinobufagin Is a Selective Anti-Cancer Agent against Tumors with EGFR Amplification and PTEN Deletion

• Główni autorzy: Kunyan He (Autor), Guang-Xing Wang (Autor), Li-Nan Zhao (Autor), Xiao-Fang Cui (Autor), Xian-Bin Su (Autor), Yi Shi (Autor), Tian-Pei Xie (Autor), Shang-Wei Hou (Autor), Ze-Guang Han (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and almost half of the patients carrying EGFR-driven tumor with PTEN deficiency are resistant to EGFR-targeted therapy. EGFR amplification and/or mutation is reported in various epithelial tumors. This series of studies aime...