METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung

• Main Authors: Cheng Cheng (Author), Yan Wu (Author), Tian Xiao (Author), Junchao Xue (Author), Jing Sun (Author), Haibo Xia (Author), Huimin Ma (Author), Lu Lu (Author), Junjie Li (Author), Aimin Shi (Author), Tao Bian (Author), Qizhan Liu (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

N6-methyladenosine (m6A) is an epigenetic modification associated with various tumors, but its role in tumorigenesis remains unexplored. Here, as confirmed by methylated RNA immunoprecipitation sequencing (meRIP-seq) and RNA sequencing (RNA-seq) analyses, exposure of human bronchial epithelial (HBE)...