The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model.

• 主要な著者: Joanna Zmurko (著者), Rafael E Marques (著者), Dominique Schols (著者), Erik Verbeken (著者), Suzanne J F Kaptein (著者), Johan Neyts (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Zika virus (ZIKV) is an emerging flavivirus typically causing a dengue-like febrile illness, but neurological complications, such as microcephaly in newborns, have potentially been linked to this viral infection. We established a panel of in vitro assays to allow the identification of ZIKV inhibitor...