Beyond Small Molecules: Antibodies and Peptides for Fibroblast Activation Protein Targeting Radiopharmaceuticals

• Main Authors: Xiaona Sun (Author), Yuxuan Wu (Author), Xingkai Wang (Author), Xin Gao (Author), Siqi Zhang (Author), Zhicheng Sun (Author), Ruping Liu (Author), Kuan Hu (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibroblast activation protein (FAP) is a serine protease characterized by its high expression in cancer-associated fibroblasts (CAFs) and near absence in adult normal tissues and benign lesions. This unique expression pattern positions FAP as a prospective biomarker for targeted tumor radiodiagnosis...