Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells

• Main Authors: Wang Yongwei (Author), Wang Jian (Author), Cheng Linan (Author), Chen Junling (Author), Sun Xiaoxi (Author), Chen Qiuju (Author), Sun Zhaogui (Author)
• Format: Book
• Published: BMC, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Ovarian granulosa cells are the predominant source of estradiol and progesterone biosynthesis in vivo. Rosiglitazone, a synthetic agonist of the peroxisome proliferator-activated receptor gamma (PPAR gamma), is applied as the treatme...