Oridonin restores hepatic lipid homeostasis in an LXRα-ATGL/EPT1 axis-dependent manner

• Main Authors: Yulian Chen (Author), Huanguo Jiang (Author), Zhikun Zhan (Author), Jindi Lu (Author), Tanwei Gu (Author), Ping Yu (Author), Weimin Liang (Author), Xi Zhang (Author), Shilong Zhong (Author), Lan Tang (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatosteatosis is characterized by abnormal accumulation of triglycerides (TG), leading to prolonged and chronic inflammatory infiltration. To date, there is still a lack of effective and economical therapies for hepatosteatosis. Oridonin (ORI) is a major bioactive component extracted from the trad...