Possible Involvement of HSP90-HSF1 Multichaperone Complex in Impairment of HSP72 Induction in the Failing Heart Following Myocardial Infarction in Rats

• Ngā kaituhi matua: Tetsuro Marunouchi (Author), Masato Araki (Author), Mao Murata (Author), Norio Takagi (Author), Kouichi Tanonaka (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2013-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

It is generally accepted that an increase in the myocardial level of heat-shock protein 72 (HSP72) protects viable cardiac tissue against myocardial infarction (MI)-induced stress. However, the induction of HSP72 after exposure to heat shock (HS) is blunted in the failing rat heart following MI. The...