Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia

• 主要な著者: Jorge del-Pozo (著者), Neil MacIntyre (著者), Ali Azar (著者), Denis Headon (著者), Pascal Schneider (著者), Michael Cheeseman (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2019-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Patients with mutations in the ectodysplasin receptor signalling pathway genes - the X-linked ligand ectodysplasin-A (EDA), the receptor EDAR or the receptor adapter EDARADD - have hypohidrotic ectodermal dysplasia (HED). In addition to having impaired development of teeth, hair, eccrine sweat gland...