Soyasaponins from Zolfino bean as aldose reductase differential inhibitors

• Main Authors: Francesco Balestri (Author), Marinella De Leo (Author), Carlo Sorce (Author), Mario Cappiello (Author), Luca Quattrini (Author), Roberta Moschini (Author), Carlotta Pineschi (Author), Alessandra Braca (Author), Concettina La Motta (Author), Federico Da Settimo (Author), Antonella Del-Corso (Author), Umberto Mura (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Seven triterpenoid saponins were identified in methanolic extracts of seeds of the Zolfino bean landrace (Phaseolus vulgaris L.) by HPLC fractionation, revealing their ability to inhibit highly purified human recombinant aldose reductase (hAKR1B1). Six of these compounds were associated by MS analys...