Traditional and Computational Screening of Non-Toxic Peptides and Approaches to Improving Selectivity

• Main Authors: Alberto A. Robles-Loaiza (Author), Edgar A. Pinos-Tamayo (Author), Bruno Mendes (Author), Josselyn A. Ortega-Pila (Author), Carolina Proaño-Bolaños (Author), Fabien Plisson (Author), Cátia Teixeira (Author), Paula Gomes (Author), José R. Almeida (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or diagnostic tools of high therapeutic value. However, only a handful have progressed to the market. Toxicity is one of the main obstacles to translating peptides into clinics. Hemolysis or hemotoxicity, the princip...