Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration

• Main Authors: Fakhar ud Din (Author), Ju Yeon Choi (Author), Dong Wuk Kim (Author), Omer Mustapha (Author), Dong Shik Kim (Author), Raj Kumar Thapa (Author), Sae Kwang Ku (Author), Yu Seok Youn (Author), Kyung Taek Oh (Author), Chul Soon Yong (Author), Jong Oh Kim (Author), Han-Gon Choi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intravenously administered for the treatment of rectum cancer, irinotecan produces severe side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double reverse thermosensitive nanocarrier system (DRTN) for rectal administration was developed as an alternative. The DRTN...