The Modulation of Interferon Regulatory Factor-1 via Caspase-1-Mediated Alveolar Macrophage Pyroptosis in Ventilator-Induced Lung Injury

Background. To examine the role of interferon regulatory factor-1 (IRF-1) and to explore the potential molecular mechanism in ventilator-induced lung injury. Methods. Wild-type C57BL/6 mice and IRF-1 gene knockout mice/caspase-1 knockout mice were mechanically ventilated with a high tidal volume to...

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Main Authors: Minhui Dai (Author), Qian Li (Author), Pinhua Pan (Author)
Format: Book
Published: Hindawi Limited, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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