Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers

• Main Authors: Lulu Chen (Author), Luping Zhou (Author), Jie Huang (Author), Yaqin Wang (Author), Guoping Yang (Author), Zhirong Tan (Author), Yicheng Wang (Author), Gan Zhou (Author), Jianwei Liao (Author), Dongsheng Ouyang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objectives: Ginsenoside compound K (CK) is a candidate drug for rheumatoid arthritis therapy. The objective of this study was to investigate the pharmacokinetic properties, safety and tolerability of CK.Methods: In randomized, double-blind trials, 76 healthy Chinese subjects received...