Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43

• Main Authors: Yuri Cho (Author), Jung-Hwan Yoon (Author), Jeong-ju Yoo (Author), Minjong Lee (Author), Dong Hyeon Lee (Author), Eun Ju Cho (Author), Jeong-Hoon Lee (Author), Su Jong Yu (Author), Yoon Jun Kim (Author), Chung Yong Kim (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fucoidan is a traditional Chinese medicine suggested to possess anti-tumor effects. In this study the anti-metastatic effects of fucoidan were investigated in vitro in human hepatocellular carcinoma (HCC) cells (Huh-7 and SNU-761) under normoxic and hypoxic conditions and in vivo using a distant liv...