Anticancer drug discovery by targeting cullin neddylation
Protein neddylation is a post-translational modification which transfers the ubiquitin-like protein NEDD8 to a lysine residue of the target substrate through a three-step enzymatic cascade. The best-known substrates of neddylation are cullin family proteins, which are the core component of Cullin-RI...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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