The Suppressive Effect of Leucine-Rich Glioma Inactivated 3 (LGI3) Peptide on Impaired Skin Barrier Function in a Murine Model Atopic Dermatitis

• Main Authors: Ui Seok Kim (Author), Jin Woo Park (Author), Eon Sub Park (Author), Joon Seok Bang (Author), Tae Woo Jung (Author), Dong-Seok Kim (Author), A. M. Abd El-Aty (Author), Jong Hyuk Lee (Author), Ji Hoon Jeong (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to restore the skin barrier function from atopic dermatitis (AD) via treatment with leucine-rich glioma inactivated 3 (LGI3) peptide. Male NC/Nga mice (7 weeks, 20 g) were randomly allocated into three groups (control, AD, and LGI3 group). After induction of AD skin lesions with <...