Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation

• Главные авторы: Melissa R. Iñigo (Автор), Adam J. Amorese (Автор), Michael D. Tarpey (Автор), Nicholas P. Balestrieri (Автор), Keith G. Jones (Автор), Daniel J. Patteson (Автор), Kathryn C. Jackson (Автор), Maria.J. Torres (Автор), Chien-Te Lin (Автор), Cody D. Smith (Автор), Timothy D. Heden (Автор), Shawna L. McMillin (Автор), Luke A. Weyrauch (Автор), Erin C. Stanley (Автор), Cameron A. Schmidt (Автор), Brita B. Kilburg-Basnyat (Автор), Sky W. Reece (Автор), Christine E. Psaltis (Автор), Leslie A. Leinwand (Автор), Katsu Funai (Автор), Joseph M. McClung (Автор), Kymberly M. Gowdy (Автор), Carol A. Witczak (Автор), Dawn A. Lowe (Автор), P. Darrell Neufer (Автор), Espen E. Spangenburg (Автор)
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• Опубликовано: Elsevier, 2020-04-01T00:00:00Z.
• Предметы: article
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Objective: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skeletal muscle were confounded by altered developmental pr...