Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation

• Main Authors: Melissa R. Iñigo (Author), Adam J. Amorese (Author), Michael D. Tarpey (Author), Nicholas P. Balestrieri (Author), Keith G. Jones (Author), Daniel J. Patteson (Author), Kathryn C. Jackson (Author), Maria.J. Torres (Author), Chien-Te Lin (Author), Cody D. Smith (Author), Timothy D. Heden (Author), Shawna L. McMillin (Author), Luke A. Weyrauch (Author), Erin C. Stanley (Author), Cameron A. Schmidt (Author), Brita B. Kilburg-Basnyat (Author), Sky W. Reece (Author), Christine E. Psaltis (Author), Leslie A. Leinwand (Author), Katsu Funai (Author), Joseph M. McClung (Author), Kymberly M. Gowdy (Author), Carol A. Witczak (Author), Dawn A. Lowe (Author), P. Darrell Neufer (Author), Espen E. Spangenburg (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skeletal muscle were confounded by altered developmental pr...