PEGylated magnetic nanographene oxide for targeted delivery of arsenic trioxide and sec-o-glucosylhamaudol in tumor treatment with improved dual-drugs synergistic effect

• Κύριοι συγγραφείς: Jinlai Cheng (Συγγραφέας), Kun Hong (Συγγραφέας), Jianhui Sun (Συγγραφέας), Hongmei Li (Συγγραφέας), Yu Zhao (Συγγραφέας), Qinghe Zhao (Συγγραφέας), Yuqing Tan (Συγγραφέας), Miyi Yang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: SpringerOpen, 2023-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Arsenic trioxide (ATO) is a promising chemotherapeutic agent, but its clinical application is limited due to its poor pharmacokinetics and dose-limited toxicity. Moreover, the combination of ATO and sec-o-glucosylhamaudol (SOG) can improve the therapeutic effect of hepatoma. In this study,...