Tree-Based QSAR Model for Drug Repurposing in the Discovery of New Antibacterial Compounds against <i>Escherichia coli</i>

• मुख्य लेखकों: Beatriz Suay-Garcia (लेखक), Antonio Falcó (लेखक), J. Ignacio Bueso-Bordils (लेखक), Gerardo M. Anton-Fos (लेखक), M. Teresa Pérez-Gracia (लेखक), Pedro A. Alemán-López (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Drug repurposing appears as an increasing popular tool in the search of new treatment options against bacteria. In this paper, a tree-based classification method using Linear Discriminant Analysis (LDA) and discrete indexes was used to create a QSAR (Quantitative Structure-Activity Relationship) mod...