Deletion of the mitochondrial calcium uniporter in adipose tissue promotes energy expenditure and alleviates diet-induced obesity

• Main Authors: Mengting Jia (Author), Siqi Liu (Author), Yang Xiao (Author), Zhiwang Zhang (Author), Mingming Li (Author), Xinyu Qi (Author), Xinyi Qi (Author), Lin Yu (Author), Caiyong Zhang (Author), Tianyu Jiang (Author), Tingli Pan (Author), Yu Sun (Author), Jingsu Yu (Author), Songtao Su (Author), Yixing Li (Author), Turtushikh Damba (Author), Khongorzul Batchuluun (Author), Yunxiao Liang (Author), Lei Zhou (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Studies have shown a correlation between obesity and mitochondrial calcium homeostasis, yet it is unclear whether and how Mcu regulates adipocyte lipid deposition. This study aims to provide new potential target for the treatment of obesity and related metabolic diseases, and to explore t...