Bavachin Protects Human Aortic Smooth Muscle Cells Against β-Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β-Catenin Signaling

• Main Authors: Hu-Qiang He (Author), Betty Yuen Kwan Law (Author), Ni Zhang (Author), Cong-ling Qiu (Author), Yuan-Qing Qu (Author), An-Guo Wu (Author), Yu Han (Author), Qi Song (Author), Wen-Lu Zheng (Author), Yong Liu (Author), Yan-Zheng He (Author), Vincent Kam Wai Wong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular calcification is a major complication of cardiovascular disease and chronic renal failure. Autophagy help to maintain a stable internal and external environment that is important for modulating arteriosclerosis, but its pathogenic mechanism is far from clear. Here, we aimed to identify the...