A Novel and Highly Selective Epidermal Growth Factor Receptor Inhibitor, SMUZ106, for the Treatment of Glioblastoma

• Main Authors: Ying Jiang (Author), Chunhui Huang (Author), Yaqi Huang (Author), Lifan Long (Author), Guowu Wu (Author), Fengqiu Guo (Author), Chuan Huang (Author), Siming Liu (Author), Zhengguang Zhu (Author), Shaoyu Wu (Author), Zhonghuang Li (Author), Jiajie Zhang (Author), Shanhe Wan (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting the epidermal growth factor receptor (EGFR) is one of the potential ways to treat glioblastoma (GBM). In this study, we investigate the anti-GBM tumor effects of the EGFR inhibitor SMUZ106 in both in vitro and in vivo conditions. The effects of SMUZ106 on the growth and proliferation of GB...