Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis

• Main Authors: Ying Wen (Author), Xiuli Zhang (Author), Lihui Wei (Author), Meizhu Wu (Author), Ying Cheng (Author), Huifang Zheng (Author), Aling Shen (Author), Changgeng Fu (Author), Farman Ali (Author), Linzi Long (Author), Yao Lu (Author), Jiapeng Li (Author), Jun Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Gastrodin has been widely used clinically in China as an antihypertensive drug. However, its effect on hypertensive renal injury is yet to be elucidated. The current study aimed to investigate the effects of gastrodin on hypertensive renal injury and its underlying mechanisms by network...