Selectively enhancing radiosensitivity of cancer cells via in situ enzyme-instructed peptide self-assembly

• Main Authors: Yang Gao (Author), Jie Gao (Author), Ganen Mu (Author), Yumin Zhang (Author), Fan Huang (Author), Wenxue Zhang (Author), Chunhua Ren (Author), Cuihong Yang (Author), Jianfeng Liu (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The radiotherapy modulators used in clinic have disadvantages of high toxicity and low selectivity. For the first time, we used the in situ enzyme-instructed self-assembly (EISA) of a peptide derivative (Nap-GDFDFpYSV) to selectively enhance the sensitivity of cancer cells with high alkaline phospha...