Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival

• Main Authors: Jingtao Jiang (Author), Jie Jin (Author), Junsheng Lou (Author), Jiafeng Li (Author), Hongqiang Wu (Author), Sheng Cheng (Author), Chengji Dong (Author), Hongyu Chen (Author), Weiyang Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Random-pattern skin flap replantation is generally used in the reconstruction of surgical tissues and covering a series of skin flap defects. However, ischemia often occurs at the flap distal parts, which lead to flap necrosis. Previous studies have shown that andrographolide (Andro) protects agains...