Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells

• Main Authors: Erik Bathoorn (Author), Paul Daly (Author), Birgit Gaiser (Author), Karl Sternad (Author), Craig Poland (Author), William MacNee (Author), Ellen M. Drost (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Gastroesophageal reflux has been associated with chronic inflammatory diseases and may be a cause of airway remodelling. Aspiration of gastric fluids may cause damage to airway epithelial cells, not only because acidity is toxic to bronchial epithelial cells, but also since it contains...