Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells

• Główni autorzy: Erik Bathoorn (Autor), Paul Daly (Autor), Birgit Gaiser (Autor), Karl Sternad (Autor), Craig Poland (Autor), William MacNee (Autor), Ellen M. Drost (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2011-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Introduction. Gastroesophageal reflux has been associated with chronic inflammatory diseases and may be a cause of airway remodelling. Aspiration of gastric fluids may cause damage to airway epithelial cells, not only because acidity is toxic to bronchial epithelial cells, but also since it contains...