Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity

• Main Authors: Klawitter Marina (Author), Quero Lilian (Author), Klasen Juergen (Author), Gloess Alexia N (Author), Klopprogge Babette (Author), Hausmann Oliver (Author), Boos Norbert (Author), Wuertz Karin (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>As proinflammatory cytokines seem to play a role in discogenic back pain, substances exhibiting anti-inflammatory effects on intervertebral disc cells may be used as minimal-invasive therapeutics for intradiscal/epidural injection. T...