Sodium alginate coating simultaneously increases the biosafety and immunotherapeutic activity of the cationic mRNA nanovaccine

• Main Authors: Xing Duan (Author), Yi Zhang (Author), Mengran Guo (Author), Na Fan (Author), Kepan Chen (Author), Shugang Qin (Author), Wen Xiao (Author), Qian Zheng (Author), Hai Huang (Author), Xiawei Wei (Author), Yuquan Wei (Author), Xiangrong Song (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The extraordinary advantages associated with mRNA vaccines, including their high efficiency, relatively low severity of side effects, and ease of manufacture, have enabled them to be a promising immunotherapy approach against various infectious diseases and cancers. Nevertheless, most mRNA delivery...