Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms

• Główni autorzy: Markus Wortmann (Autor), Muhammad Arshad (Autor), Maani Hakimi (Autor), Dittmar Böckler (Autor), Susanne Dihlmann (Autor)
• Format: Książka
• Wydane: BMC, 2020-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Phenotypic transformation of vascular smooth muscle cells is a key element in vascular remodeling and aortic aneurysm growth. Previously, deletion of several inflammasome components decreased formation of aortic aneurysm (AA) in the Angiotensin II (AngII) -induced mouse model. We...