Physicochemical Investigation of Psoralen Binding to Double Stranded DNA through Electroanalytical and Cheminformatic Approaches

• Main Authors: Douglas Vieira Thomaz (Author), Matheus Gabriel de Oliveira (Author), Edson Silvio Batista Rodrigues (Author), Vinicius Barreto da Silva (Author), Pierre Alexandre dos Santos (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work showcased the first physicochemical investigation of psoralen (PSO) binding to double stranded DNA (dsDNA) through electroanalytical methods. Results evidenced that PSO presents one non-reversible anodic peak at electric potential (<i>E</i>_pa) ≈ 1.42 V, w...