Protective Effect and Possible Mechanisms of Astragaloside IV in Animal Models of Diabetic Nephropathy: A Preclinical Systematic Review and Meta-Analysis

• Main Authors: Hong Wang (Author), Zhuang Zhuang (Author), Yue-Yue Huang (Author), Zhi-Zhi Zhuang (Author), Yi Jin (Author), Han-Yang Ye (Author), Xiao-Ji Lin (Author), Qun Zheng (Author), Yi-Luan Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Astragaloside IV (AS-IV) has a variety of biological activities and is widely used to treat kidney diseases. We conducted a systematic review of 24 animal studies including 424 animals to evaluate the efficacy of AS-IV for diabetic nephropathy (DN); all current possible mechanisms were summarized. A...