Can ivermectin mass treatments eliminate onchocerciasis in Africa?

• Main Authors: M. Winnen (Author), A.P. Plaisier (Author), E.S. Alley (Author), N.J.D. Nagelkerke (Author), G. van Oortmarssen (Author), B.A. Boatin (Author), J.D.F. Habbema (Author)
• Format: Book
• Published: The World Health Organization.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE: To elucidate the conditions in which mass treatment with ivermectin reduces the transmission of Onchocerca volvulus sufficiently to eliminate infection from an African community. METHODS: ONCHOSIM, a microsimulation model for onchocerciasis transmission, was used to explore the implicatio...