Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

• Main Authors: Alison C. McGarvey (Author), Wolfgang Kopp (Author), Dubravka Vučićević (Author), Kenny Mattonet (Author), Rieke Kempfer (Author), Antje Hirsekorn (Author), Ilija Bilić (Author), Marine Gil (Author), Alexandra Trinks (Author), Anne Margarete Merks (Author), Daniela Panáková (Author), Ana Pombo (Author), Altuna Akalin (Author), Jan Philipp Junker (Author), Didier Y.R. Stainier (Author), David Garfield (Author), Uwe Ohler (Author), Scott Allen Lacadie (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While many genes regulating embryonic development have been identified, the underlying CRE dynamics controlling their expression remain largely uncharact...