Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

• المؤلفون الرئيسيون: Alison C. McGarvey (مؤلف), Wolfgang Kopp (مؤلف), Dubravka Vučićević (مؤلف), Kenny Mattonet (مؤلف), Rieke Kempfer (مؤلف), Antje Hirsekorn (مؤلف), Ilija Bilić (مؤلف), Marine Gil (مؤلف), Alexandra Trinks (مؤلف), Anne Margarete Merks (مؤلف), Daniela Panáková (مؤلف), Ana Pombo (مؤلف), Altuna Akalin (مؤلف), Jan Philipp Junker (مؤلف), Didier Y.R. Stainier (مؤلف), David Garfield (مؤلف), Uwe Ohler (مؤلف), Scott Allen Lacadie (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2022-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Summary: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While many genes regulating embryonic development have been identified, the underlying CRE dynamics controlling their expression remain largely uncharact...