Transferrin-Conjugated Polymeric Nanoparticle for Receptor-Mediated Delivery of Doxorubicin in Doxorubicin-Resistant Breast Cancer Cells

• Main Authors: Zar Chi Soe (Author), Jun Bum Kwon (Author), Raj Kumar Thapa (Author), Wenquan Ou (Author), Hanh Thuy Nguyen (Author), Milan Gautam (Author), Kyung Taek Oh (Author), Han-Gon Choi (Author), Sae Kwang Ku (Author), Chul Soon Yong (Author), Jong Oh Kim (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, a transferrin (T_f)-conjugated polymeric nanoparticle was developed for the targeted delivery of the chemotherapeutic agent doxorubicin (Dox) in order to overcome multi-drug resistance in cancer treatment. Our objective was to improve Dox delivery for producing s...