Development of quantification methods of a new selective carbonic anhydrase II inhibitor in plasma and blood and study of the pharmacokinetics of its ophthalmic suspension in rats

• Главные авторы: Alexander L. Khokhlov (Автор), Ilya I. Yaichkov (Автор), Mikhail K. Korsakov (Автор), Anton A. Shetnev (Автор), Nikita N. Volkhin (Автор), Sergey S. Petukhov (Автор)
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• Опубликовано: Belgorod National Research University, 2023-11-01T00:00:00Z.
• Предметы: article
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Introduction: Development of new bioanalytical methods is required for studying the systemic exposure of new selective inhibitor of carbonic anhydrase II, 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide, and its N-hydroxymetabolite in plasma and in whole blood. The results of the experiment with a...