Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2

• Main Authors: Craig M. Keenan (Author), Lorenzo Ramos-Mucci (Author), Ioannis Kanakis (Author), Peter I. Milner (Author), Andrew Leask (Author), David Abraham (Author), George Bou-Gharios (Author), Blandine Poulet (Author)
• Format: Book
• Published: The Company of Biologists, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CCN2 is a matricellular protein involved in several crucial biological processes. In particular, CCN2 is involved in cartilage development and in osteoarthritis. Ccn2 null mice exhibit a range of skeletal dysmorphisms, highlighting its importance in regulating matrix formation during development; ho...