Inhibition of the Glycine Receptor alpha 3 Function by Colchicine

• Main Authors: Carola Muñoz-Montesino (Author), Carlos F. Burgos (Author), Cesar O. Lara (Author), Camila R. Riquelme (Author), David Flaig (Author), Victoria P. San Martin (Author), Luis G. Aguayo (Author), Jorge Fuentealba (Author), Patricio A. Castro (Author), Leonardo Guzmán (Author), Gonzalo E. Yévenes (Author), Gustavo Moraga-Cid (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colchicine is a plant alkaloid that is widely used as a therapeutic agent. It is widely accepted that colchicine reduces the production of inflammatory mediators mainly by altering cytoskeleton dynamics due to its microtubule polymerization inhibitory activity. However, other lines of evidence have...