Lysophosphatidylcholine Increases Na+/Ca2+ Exchanger Expression via RhoB-Geranylgeranylation in H9c2 Cells

• Hlavní autoři: Sachiko Maeda (Autor), Kazuho Sakamoto (Autor), Isao Matsuoka (Autor), Takahiro Iwamoto (Autor), Junko Kimura (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2009-01-01T00:00:00Z.
• Témata: article
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The expression levels of the Na+/Ca2+ exchanger type 1 (NCX1) change under various cardiac pathophysiological conditions, but the mechanism is unknown. We previously demonstrated that lysophosphatidylcholine (LPC) increased NCX1 expression by activating RhoB in H9c2 cardiomyoblasts. Conversely, fluv...