Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents

• Main Authors: Ines Maestro (Author), Enrique Madruga (Author), Patricia Boya (Author), Ana Martínez (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases, there are no reported inhibitors...