Microwave-assisted Phospha-Michael addition reactions in the 13α-oestrone series and in vitro antiproliferative properties

• Hoofdauteurs: Erzsébet Mernyák (Auteur), Sándor Bartha (Auteur), Lili Kóczán (Auteur), Rebeka Jójárt (Auteur), Vivien Resch (Auteur), Gábor Paragi (Auteur), Máté Vágvölgyi (Auteur), Attila Hunyadi (Auteur), Bella Bruszel (Auteur), István Zupkó (Auteur), Renáta Minorics (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Microwave-assisted phospha-Michael addition reactions were carried out in the 13α-oestrone series. The exocyclic 16-methylene-17-ketones as α,β-unsaturated ketones were reacted with secondary phosphine oxides as nucleophilic partners. The addition reactions furnished the two tertiary phosphine oxide...